Biotin and derivatives
Medchemexpress LLC Diazo biotin-PEG3-azide | 1339202-33-3 | MFCD28334530 | 95.5% | C33H45N9O7S | 10MG
Diazo biotin-PEG3-azide is a multifunctional PEG3 linker combining a cleavable diazo functional group, a biotin affinity tag, and an azide reactive handle. It is designed for efficient biotinylation and capture of alkyne-bearing biomolecules using click chemistry and for use as a linker in chemical biology workflows.
- Provides azide functionality for CuAAC and SPAAC click reactions.
- Includes a biotin tag for affinity purification and detection.
- Contains a diazo group enabling photo-cleavage or crosslinking.
- PEG3 spacer improves solubility and reduces steric hindrance.
- Suitable for biotinylation, pull-down assays, and linker synthesis.
eMolecules Combi-Blocks Mal-PEG2-NHS ester 100mg 303339072 QI-6954 98 000 1433997-01-3 MFCD24539465 354 315 C15H18N2O8
Combi-Blocks Mal-PEG2-NHS ester 100mg 303339072 QI-6954 98 000 1433997-01-3 MFCD24539465 354 315 C15H18N2O8
Medchemexpress LLC Azido-PEG6-NHS ester | 2055014-64-5 | 98.0% | 1 G
Azido-PEG6-NHS ester is a cleavable 6 unit PEG ADC linker utilized in the synthesis of antibody-drug conjugates (ADCs). It also functions as a PEG- and Alkyl/ether based PROTAC linker for synthesizing PROTACs. This compound is a click chemistry reagent, featuring an Azide group, which allows it to participate in copper-catalyzed azide-alkyne cycloaddition reactions (CuAAc) with molecules containing Alkyne groups. Additionally, it can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
- Cleavable linker
- PEG linker type
- Alkyl/ether linker type
- Click chemistry reagent
- Contains an azide group
- Participates in copper-catalyzed azide-alkyne cycloaddition reactions
- Undergoes strain-promoted alkyne-azide cycloaddition reactions
- Used in ADC synthesis
- Used in PROTAC synthesis
Medchemexpress LLC Acid-C2-PEG4-C2-NHS ester | 1343476-41-4 | 98.0% | 100 MG
Acid-C2-PEG4-C2-NHS ester is a PEG-based PROTAC linker. This chemical reagent is used in the synthesis of PROTACs and is intended for research use only. It appears as a colorless to light yellow liquid.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Exploits the intracellular ubiquitin-proteasome system
- Designed for selective degradation of target proteins
- Consists of two different ligands connected by a linker
- One ligand binds to an E3 ubiquitin ligase, the other to the target protein
Medchemexpress LLC Biotin-DADOO (Biotinyl-3,6-dioxaoctanediamine) | 138529-46-1 | 98.0% | 500 MG
Biotin-DADOO is a biotin-containing amine compound and a biotinylation reagent. It acts as an amino component in the nucleophilic ring-opening reaction of epoxidized ω-double bonds during the synthesis of biotinylated inhibitor derivatives. This product can be conjugated with carboxymethyl cellulose derivatives and is involved in the synthesis of biotin-estradiol conjugates for enzyme immunoassays. It can also be utilized in influenza A research.
- Captures free influenza neuraminidase on streptavidin-coated polystyrene plates.
- Forms stable self-assembled monolayers (SAMs) on planar gold surfaces.
- Forms a stable biotin-estradiol conjugate.
Apexbio Technology LLC Biotin-16-dUTP(Synonyms: Biotin-16-2'-deoxyuridine-5'-triphosphate, Biotin-16-dUTP nucleotide), 10ul (5 mM).
Biotin-16-dUTP is a biotin-labeled nucleotide analog utilized extensively in biomedical research for nucleic acid modification and detection Structurally modified to contain a biotin moiety linked via a 16-carbon spacer this compound functions by enzymatic incorporation into DNA strands mediated by DNA polymerases Following integration the biotin group serves as an affinity tag enabling subsequent detection through biotin-binding proteins such as streptavidin Applications include DNA labeling techniques in fluorescence microscopy and flow cytometry facilitating the visualization and analysis of nucleic acids in vitro
Medchemexpress LLC Biotin-DADOO TFA | 194920-57-5 | 95.0% | 250 MG
Biotin-DADOO TFA is a biotinylating reagent that is conjugated to CMC thiosulfate.
- Can be utilized to synthesize biotin-estradiol conjugates.
- Used for the determination of plasma estradiol concentrations by enzyme immunoassay.
- Appearance: oil.
- Color: light yellow to brown.
- For research use only.
Medchemexpress LLC (+)-Biotin-SLC | 1864003-57-5 | ≥97.0% | 50 MG
(+)-Biotin-SLC is an alkyl chain-based PROTAC linker designed for use in the synthesis of PROTACs. These molecules contain two different ligands connected by a linker: one targeting an E3 ubiquitin ligase and the other for a specific target protein. PROTACs leverage the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- Alkyl chain-based PROTAC linker
- Used in the synthesis of PROTACs
- Exploits the intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
- For research use only
Medchemexpress LLC Biotin-PEG4-acid | 721431-18-1 | 97.0% | 100 MG
Biotin-PEG4-acid is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. PROTACs (Proteolysis Targeting Chimeras) are compounds with two ligands connected by a linker; one binds to an E3 ubiquitin ligase, and the other targets a specific protein, exploiting the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- Peg-based protac linker
- Can be utilized in the synthesis of protacs
- Has a purity of 97.0%
- Appears as a white to off-white solid
- Intended for research use only
Medchemexpress LLC Biotin N-hydroxysuccinimide ester | 35013-72-0 | 99.9% | 200 MG
Biotin NHS is an amino reactive biotin reagent utilized in the preparation of biotinylated surfaces or polypeptides. It can function as a chemical label for polypeptides and nanocarriers, and is also suitable for labeling biotinylated viruses. This compound is unstable in solutions, therefore freshly prepared solutions are recommended for optimal results.
- Amino reactive biotin reagent
- Can be used as a chemical label for polypeptide and nanocarrier
- Suitable for labeling biotinylated virus
Medchemexpress LLC BHQ-2 NHS | 916753-62-3 | 97.7% | 603.58 | 50 MG
BHQ-2 NHS is a dark quencher with no native emission due to the polyaromatic-azo backbone and a terminal NHS ester. It has a wide and intense quenching range from 560-670 nm, making it useful as an acceptor in fluorescence resonance energy transfer (FRET) applications with orange to far-red emitting dyes. The NHS ester can be used to label primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules.
- Dark quencher with no native emission due to the polyaromatic-azo backbone and a terminal NHS ester.
- Wide and intense quenching range from 560-670 nm.
- Useful as an acceptor in fluorescence resonance energy transfer (FRET) applications in conjunction with orange to far-red emitting dyes.
- NHS ester can be applied to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules.
Medchemexpress LLC Biotin-TEG-ATFBA | 1264662-85-2 | MFCD13184978 | 99.1% | 663.68 | C27H37F4N7O6S | 10 MG
Biotin-TEG-ATFBA is a biotin-labeled click chemistry reagent containing a perfluorophenylazide group. Upon photolysis it forms a stable azene intermediate that participates in insertion and cycloaddition reactions, enabling bioconjugation and linker construction for research applications. The compound is supplied as a solid with high purity and is intended for laboratory use.
Medchemexpress LLC Dota-NHS-ester TFA | 95.0% | 25 MG
DOTA-NHS-ester (TFA) is a versatile linker for affibody molecules, essential in various imaging techniques such as small animal positron emission tomography (PET), single photon emission computed tomography (SPECT), and CT scanning. It is also used for labeling radiotracers or imaging probes, particularly for tumor detection research.
- Used as a linker for affibody molecules
- Applicable in small animal PET, SPECT, and CT scanning
- Labels radiotracers or imaging probes for tumor detection
- For research use only
- Supplied as a solid, white to off-white in color
- Molecular weight: 615.51
- Formula: C22H32F3N5O12
- Storage: -20°C, sealed, away from moisture
- Solubility (in vitro): DMSO at 125 mg/mL (203.08 mM), requires ultrasonic
Medchemexpress LLC M-PEG16-NHS ester | 2563873-83-4 | MFCD13184971 | ≥97.0% | 861.97 | C38H71NO20 | 250mg
m-PEG16-NHS ester is a PEG derivative composed of an NHS ester that can be conjugated to amino acids or other molecules containing amino groups[1]